EMD-32119

Single-particle
3.23 Å
EMD-32119
3D View Gallery
Deposition: 30/10/2021
Map released: 09/03/2022
Last modified: 26/06/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-32119
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7vtp summary report (pdf.gz) Map and 7vtp FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of PYD-deleted human NLRP3 hexamer

EMD-32119

Single-particle
3.23 Å
EMD-32119
3D View Gallery
Deposition: 30/10/2021
Map released: 09/03/2022
Last modified: 26/06/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: human NLRP3 (PYD-deleted) hexamer
Fitted models: 7vtp

Deposition Authors: Ohto U, Shimizu T
Structural basis for the oligomerization-mediated regulation of NLRP3 inflammasome activation.
Ohto U, Kamitsukasa Y , Ishida H, Zhang Z, Murakami K, Hirama C, Maekawa S, Shimizu T
(2022) PNAS , 119 , e2121353119 - e2121353119
PUBMED: 35254907
DOI: doi:10.1073/pnas.2121353119
ISSN: 1091-6490
ASTM: PNASA6