EMD-31537

Single-particle
4.0 Å
EMD-31537
3D View Gallery
Deposition: 16/07/2021
Map released: 08/09/2021
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-31537
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7fd9 summary report (pdf.gz) Map and 7fd9 FULL report (pdf.gz)
EMICSS annotations (xml)

Thermostabilised full length human mGluR5-5M with orthosteric antagonist, LY341495

EMD-31537

Single-particle
4.0 Å
EMD-31537
3D View Gallery
Deposition: 16/07/2021
Map released: 08/09/2021
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human FL mGluR5-5M with orthosteric antagonist LY341495 and NAM MPEP
Fitted models: 7fd9

Deposition Authors: Vinothkumar KR, Cannone G
Agonists and allosteric modulators promote signaling from different metabotropic glutamate receptor 5 conformations.
Nasrallah C, Cannone G, Briot J , Rottier K, Berizzi AE, Huang CY, Quast RB , Hoh F , Baneres JL , Malhaire F , Berto L, Dumazer A , Font-Ingles J, Gomez-Santacana X , Catena J, Kniazeff J, Goudet C , Llebaria A, Pin JP, Vinothkumar KR, Lebon G
(2021) Cell Rep , 36 , 109648 - 109648
PUBMED: 34469715
DOI: doi:10.1016/j.celrep.2021.109648
ISSN: 2211-1247