Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-31309
Structure of the human GluN1-GluN2B NMDA receptor in complex with S-ketamine,glycine and glutamate
EMD-31309
Single-particle4.07 Å
Deposition: 16/05/2021Map released: 28/07/2021
Last modified: 06/11/2024
Sample Organism:
Homo sapiens
Sample: tetrameric complex of GluN1 and GluN2B subunits
Fitted models: 7eu8
Deposition Authors: Zhang T
,
Zhang Y
,
Zhu S
Sample: tetrameric complex of GluN1 and GluN2B subunits
Fitted models: 7eu8
Deposition Authors: Zhang T
,
Zhang Y
,
Zhu S
Structural basis of ketamine action on human NMDA receptors.
Zhang Y
,
Ye F
,
Zhang T
,
Lv S
,
Zhou L,
Du D
,
Lin H,
Guo F,
Luo C
,
Zhu S
(2021) Nature , 596 , 301 - 305
,
Ye F
,
Zhang T
,
Lv S
,
Zhou L,
Du D
,
Lin H,
Guo F,
Luo C
,
Zhu S
(2021) Nature , 596 , 301 - 305
Grant Support:
- National Natural Science Foundation of China (NSFC): 31771115 (China)
- Chinese Academy of Sciences: XDBS01020000 (China)
- National Natural Science Foundation of China (NSFC): 81625022 (China)
- National Natural Science Foundation of China (NSFC): 91853205 (China)
- National Natural Science Foundation of China (NSFC): 81821005 (China)
- National Key R&D Program of China: 2017YFA0505700 (China)
- Shanghai Municipal Health Commission in China: 18431907100 (China)
- Shanghai Municipal Health Commission in China: 19XD1404700 (China)
- Shanghai Municipal Science and Technology Major Project: 2018SHZDZX05 (China)
