Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-31061
A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase
EMD-31061
Single-particle2.98 Å
Deposition: 15/03/2021Map released: 16/02/2022
Last modified: 25/06/2025
Sample Organism:
Severe acute respiratory syndrome coronavirus 2,
synthetic construct
Sample: nsp12-nsp7-nsp8-RNA-AT9010
Fitted models: 7ed5
Deposition Authors: Shannon A
,
Fattorini V
Sample: nsp12-nsp7-nsp8-RNA-AT9010
Fitted models: 7ed5
Deposition Authors: Shannon A
,
Fattorini V
A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase.
Shannon A
,
Fattorini V,
Sama B
,
Selisko B,
Feracci M,
Falcou C
,
Gauffre P
,
El Kazzi P,
Delpal A
,
Decroly E
,
Alvarez K
,
Eydoux C
,
Guillemot JC,
Moussa A,
Good SS,
La Colla P,
Lin K
,
Sommadossi JP,
Zhu Y
,
Yan X,
Shi H
,
Ferron F,
Canard B
(2022) Nat Commun , 13 , 621 - 621
,
Fattorini V,
Sama B
,
Selisko B,
Feracci M,
Falcou C
,
Gauffre P
,
El Kazzi P,
Delpal A
,
Decroly E
,
Alvarez K
,
Eydoux C
,
Guillemot JC,
Moussa A,
Good SS,
La Colla P,
Lin K
,
Sommadossi JP,
Zhu Y
,
Yan X,
Shi H
,
Ferron F,
Canard B
(2022) Nat Commun , 13 , 621 - 621
Grant Support:
