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EMD-30952
Structure of PfFNT in apo state
EMD-30952
Single-particle2.29 Å
Deposition: 04/02/2021Map released: 18/08/2021
Last modified: 05/06/2024
Sample Organism:
Plasmodium falciparum 3D7
Sample: Pentameric complex of FNT
Fitted models: 7e26
Deposition Authors: Yan CY, Jiang X
,
Peng X,
Wang N ,
Zhu A ,
Xu H ,
Li J
Sample: Pentameric complex of FNT
Fitted models: 7e26
Deposition Authors: Yan CY, Jiang X
,
Peng X,
Wang N ,
Zhu A ,
Xu H ,
Li J
Structural characterization of the Plasmodium falciparum lactate transporter PfFNT alone and in complex with antimalarial compound MMV007839 reveals its inhibition mechanism.
Peng X,
Wang N ,
Zhu A ,
Xu H ,
Li J ,
Zhou Y,
Wang C,
Xiao Q,
Guo L,
Liu F,
Jia ZJ,
Duan H,
Hu J,
Yuan W,
Geng J,
Yan C ,
Jiang X ,
Deng D
(2021) PLoS Biol , 19 , e3001386 - e3001386
,
Zhu A ,
Xu H ,
Li J ,
Zhou Y,
Wang C,
Xiao Q,
Guo L,
Liu F,
Jia ZJ,
Duan H,
Hu J,
Yuan W,
Geng J,
Yan C ,
Jiang X ,
Deng D
(2021) PLoS Biol , 19 , e3001386 - e3001386