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EMD-30460

Single-particle
4.0 Å
EMD-30460
3D View Gallery
Deposition: 18/08/2020
Map released: 18/11/2020
Last modified: 16/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-30460
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7ct5 summary report (pdf.gz) Map and 7ct5 FULL report (pdf.gz)
EMICSS annotations (xml)

cryo EM map of the S protein of SARS-CoV-2 in complex bound with T-ACE2

EMD-30460

Single-particle
4.0 Å
EMD-30460
3D View Gallery
Deposition: 18/08/2020
Map released: 18/11/2020
Last modified: 16/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Severe acute respiratory syndrome coronavirus 2, Homo sapiens
Sample: S protein of SARS-CoV-2 in complex bound with ACE2
Fitted models: 7ct5

Deposition Authors: Guo L, Bi WW
Engineered trimeric ACE2 binds viral spike protein and locks it in "Three-up" conformation to potently inhibit SARS-CoV-2 infection.
Guo L, Bi W , Wang X, Xu W , Yan R, Zhang Y, Zhao K, Li Y, Zhang M, Cai X, Jiang S , Xie Y, Zhou Q, Lu L , Dang B
(2021) Cell Res , 31 , 98 - 100
PUBMED: 33177651
DOI: doi:10.1038/s41422-020-00438-w
ISSN: 1001-0602