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EMD-30456
NSD3 bearing E1181K/T1232A dual mutation in complex with 187-bp NCP (2:1 binding mode)
EMD-30456
Single-particle3.15 Å
Deposition: 14/08/2020Map released: 21/10/2020
Last modified: 02/07/2025
Sample Organism:
Xenopus laevis,
Homo sapiens,
Xenopus tropicalis
Sample: NSD3 bearing E1181K/T1232A dual mutation in complex with 187-bp NCP (2:1 binding mode)
Fitted models: 7crq
Deposition Authors: Li W, Tian W
Sample: NSD3 bearing E1181K/T1232A dual mutation in complex with 187-bp NCP (2:1 binding mode)
Fitted models: 7crq
Deposition Authors: Li W, Tian W
Molecular basis of nucleosomal H3K36 methylation by NSD methyltransferases.
Li W,
Tian W,
Yuan G,
Deng P,
Sengupta D
,
Cheng Z,
Cao Y,
Ren J,
Qin Y,
Zhou Y
,
Jia Y,
Gozani O
,
Patel DJ
,
Wang Z
(2021) Nature , 590 , 498 - 503
,
Cheng Z,
Cao Y,
Ren J,
Qin Y,
Zhou Y
,
Jia Y,
Gozani O
,
Patel DJ
,
Wang Z
(2021) Nature , 590 , 498 - 503
Grant Support:
- National Natural Science Foundation of China (NSFC): 31870725 (China)
- National Natural Science Foundation of China (NSFC): 31570729 (China)
- Other government: Fundamental Research Funds for the Central Universities (2017EYT19) (China)
- Other government: Memorial Sloan-Kettering Cancer Center Core grant P30CA008748 (United States)
- National Institutes of Health/National Library of Medicine (NIH/NLM): R01GM079641 (United States)
- Other government: Basic Research grant from Shenzhen government (JCYJ20180302174213122) (China)
