EMD-30312

Single-particle
3.1 Å
EMD-30312
3D View Gallery
Deposition: 05/06/2020
Map released: 27/01/2021
Last modified: 18/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-30312

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7c9i summary report (pdf.gz) Map-7c9i FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Human gamma-secretase in complex with small molecule L-685,458

EMD-30312

Single-particle
3.1 Å
EMD-30312
3D View Gallery
Deposition: 05/06/2020
Map released: 27/01/2021
Last modified: 18/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: human gamma-secretase
Fitted models: 7c9i

Deposition Authors: Yang G, Zhou R
Structural basis of gamma-secretase inhibition and modulation by small molecule drugs.
Yang G, Zhou R , Guo X, Yan C , Lei J, Shi Y
(2021) Cell , 184 , 521 - 533.e14
PUBMED: 33373587
DOI: doi:10.1016/j.cell.2020.11.049
ISSN: 1097-4172