EMD-30269

Helical reconstruction
3.8 Å
EMD-30269
3D View Gallery
Deposition: 03/05/2020
Map released: 05/05/2021
Last modified: 29/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-30269

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7c1d summary report (pdf.gz) Map-7c1d FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Cryo-EM structure of the hE46K cross-seeded hWT alpha-synuclein fibril

EMD-30269

Helical reconstruction
3.8 Å
EMD-30269
3D View Gallery
Deposition: 03/05/2020
Map released: 05/05/2021
Last modified: 29/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: the hE46K cross-seeded hWT alpha-synuclein fibril
Fitted models: 7c1d

Deposition Authors: Sun YP, Zhao K
Wild-type alpha-synuclein inherits the structure and exacerbated neuropathology of E46K mutant fibril strain by cross-seeding.
Long H , Zheng W , Liu Y , Sun Y , Zhao K , Liu Z, Xia W, Lv S, Liu Z, Li D , He KW , Liu C
(2021) PNAS , 118
PUBMED: 33972418
DOI: doi:10.1073/pnas.2012435118
ISSN: 1091-6490
ASTM: PNASA6