EMD-30074

Single-particle
3.7 Å
EMD-30074
3D View Gallery
Deposition: 06/03/2020
Map released: 20/01/2021
Last modified: 25/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-30074

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-6m49 summary report (pdf.gz) Map-6m49 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

cryo-EM structure of Scap/Insig complex in the present of 25-hydroxyl cholesterol.

EMD-30074

Single-particle
3.7 Å
EMD-30074
3D View Gallery
Deposition: 06/03/2020
Map released: 20/01/2021
Last modified: 25/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Scap and Insig complex
Fitted models: 6m49

Deposition Authors: Yan R , Cao P
A structure of human Scap bound to Insig-2 suggests how their interaction is regulated by sterols.
Yan R , Cao P , Song W , Qian H , Du X , Coates HW , Zhao X , Li Y , Gao S , Gong X , Liu X , Sui J , Lei J , Yang H , Brown AJ , Zhou Q , Yan C, Yan N
(2021) Science , 371
PUBMED: 33446483
DOI: doi:10.1126/science.abb2224
ISSN: 1095-9203
ASTM: SCIEAS