EMD-29770
Coagulation factor VIII bound to a patient-derived anti-C1 domain antibody inhibitor
EMD-29770
Single-particle4.23 Å
Deposition: 15/02/2023Map released: 24/05/2023
Last modified: 30/10/2024
Sample Organism:
Homo sapiens
Sample: Structure of coagulation factor VIII bound to a patient-derived anti-C1 domain antibody inhibitor
Fitted models: 8g6i
Deposition Authors: Childers KC
,
Davulcu O ,
Haynes RM,
Lollar P ,
Doering CB ,
Coxon CH ,
Spiegel PC
Sample: Structure of coagulation factor VIII bound to a patient-derived anti-C1 domain antibody inhibitor
Fitted models: 8g6i
Deposition Authors: Childers KC
,
Davulcu O ,
Haynes RM,
Lollar P ,
Doering CB ,
Coxon CH ,
Spiegel PC
Structure of coagulation factor VIII bound to a patient-derived anti-C1 domain antibody inhibitor.
Childers KC ,
Avery NG ,
Estrada Alamo KA,
Davulcu O ,
Haynes RM,
Lollar P ,
Doering CB ,
Coxon CH ,
Spiegel PC
(2023) Blood , 142 , 197 - 201
,
Avery NG ,
Estrada Alamo KA,
Davulcu O ,
Haynes RM,
Lollar P ,
Doering CB ,
Coxon CH ,
Spiegel PC
(2023) Blood , 142 , 197 - 201
Grant Support:
- National Institutes of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI): R15HL135658 (United States)
- National Institutes of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI): U54HL141981 (United States)
- National Institutes of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI): R44HL117511 (United States)
- National Institutes of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI): R44HL110448 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): U24GM129547 (United States)