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EMD-29741

Single-particle
2.64 Å
EMD-29741
3D View Gallery
Deposition: 13/02/2023
Map released: 20/09/2023
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-29741
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8g5f summary report (pdf.gz) Map and 8g5f FULL report (pdf.gz)
EMICSS annotations (xml)

Native GABA-A receptor from the mouse brain, ortho-alpha1-alpha3-beta2-gamma2 subtype, in complex with GABA and allopregnanolone

EMD-29741

Single-particle
2.64 Å
EMD-29741
3D View Gallery
Deposition: 13/02/2023
Map released: 20/09/2023
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus
Sample: Native GABAA Receptor isolated from mouse brain containing one alpha1 subunit, in complex with 8E3-Fab, GABA, and allopregnanolone
Fitted models: 8g5f

Deposition Authors: Sun C, Gouaux E
Cryo-EM structures reveal native GABA A receptor assemblies and pharmacology.
Sun C, Zhu H, Clark S, Gouaux E
(2023) Nature , 622 , 195 - 201
PUBMED: 37730991
DOI: doi:10.1038/s41586-023-06556-w
ISSN: 1476-4687
ASTM: NATUAS