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EMD-29735
Structure of nucleosome-bound Sirtuin 6 deacetylase
EMD-29735
Single-particle3.07 Å
Deposition: 11/02/2023Map released: 26/04/2023
Last modified: 19/06/2024
Sample Organism:
Homo sapiens,
Xenopus laevis,
synthetic construct
Sample: Sirt6 deacetylase bound to a nucleosome assembled with 172-bp 601 Widom DNA
Fitted models: 8g57
Deposition Authors: Chio US
,
Rechiche O
,
Bryll AR
,
Zhu J
,
Feldman JL
,
Peterson CL
,
Tan S
,
Armache J-P
Sample: Sirt6 deacetylase bound to a nucleosome assembled with 172-bp 601 Widom DNA
Fitted models: 8g57
Deposition Authors: Chio US
,
Rechiche O
,
Bryll AR
,
Zhu J
,
Feldman JL
,
Peterson CL
,
Tan S
,
Armache J-P
Cryo-EM structure of the human Sirtuin 6-nucleosome complex.
Chio US
,
Rechiche O
,
Bryll AR
,
Zhu J
,
Leith EM
,
Feldman JL
,
Peterson CL
,
Tan S
,
Armache JP
(2023) Sci Adv , 9 , eadf7586 - eadf7586
,
Rechiche O
,
Bryll AR
,
Zhu J
,
Leith EM
,
Feldman JL
,
Peterson CL
,
Tan S
,
Armache JP
(2023) Sci Adv , 9 , eadf7586 - eadf7586
Grant Support:
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): F32GM137463 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R35GM127034 (United States)
- National Institutes of Health/National Institute of Biomedical Imaging and Bioengineering (NIH/NIBIB): T32BM107000 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R35GM127034 (United States)
