Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-29713

Single-particle
3.02 Å
EMD-29713
3D View Gallery
Deposition: 08/02/2023
Map released: 09/08/2023
Last modified: 27/09/2023
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-29713
Download
3D volume (map.gz) Experimental metadata (xml)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8g42 summary report (pdf.gz) Map and 8g42 FULL report (pdf.gz)
EMICSS annotations (xml)

KRAS G12C complex with GDP imaged on a cryo-EM imaging scaffold

EMD-29713

Single-particle
3.02 Å
EMD-29713
3D View Gallery
Deposition: 08/02/2023
Map released: 09/08/2023
Last modified: 27/09/2023
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: synthetic construct, Homo sapiens
Sample: KRAS G12C displayed on a Cryo-EM imaging scaffold
Fitted models: 8g42

Deposition Authors: Castells-Graells R , Sawaya MR , Yeates TO
Cryo-EM structure determination of small therapeutic protein targets at 3 angstrom -resolution using a rigid imaging scaffold.
Castells-Graells R , Meador K , Arbing MA , Sawaya MR , Gee M , Cascio D , Gleave E, Debreczeni JE, Breed J, Leopold K , Patel A , Jahagirdar D , Lyons B, Subramaniam S , Phillips C , Yeates TO
(2023) PNAS , 120 , e2305494120 - e2305494120
PUBMED: 37669364
DOI: doi:10.1073/pnas.2305494120
ISSN: 1091-6490
ASTM: PNASA6