EMD-29616

Single-particle
2.85 Å
EMD-29616
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Deposition: 28/01/2023
Map released: 24/05/2023
Last modified: 06/09/2023
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-29616
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Cryo-EM map of chimeric Sec complex (human Sec61 and yeast Sec63-71-72) inhibited by cyclotriazadisulfonamide (CADA)

EMD-29616

Single-particle
2.85 Å
EMD-29616
3D View Gallery
Deposition: 28/01/2023
Map released: 24/05/2023
Last modified: 06/09/2023
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Homo sapiens, Saccharomyces cerevisiae
Sample: A human-yeast chimeric Sec complex treated with cyclotriazadisulfonamide (CADA)

Deposition Authors: Park E , Itskanov S
A common mechanism of Sec61 translocon inhibition by small molecules.
Itskanov S , Wang L , Junne T, Sherriff R , Xiao L, Blanchard N , Shi WQ , Forsyth C, Hoepfner D , Spiess M , Park E
(2023) Nat Chem Biol , 19 , 1063 - 1071
PUBMED: 37169959
DOI: doi:10.1038/s41589-023-01337-y
ISSN: 1552-4469