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EMD-29560
5-MeO-DMT-bound serotonin 1A (5-HT1A) receptor-Gi1 protein complex
EMD-29560
Single-particle2.79 Å
Deposition: 25/01/2023Map released: 15/05/2024
Last modified: 30/10/2024
Sample Organism:
Homo sapiens,
Escherichia coli, Homo sapiens
Sample: Serotonin 1A (5-HT1A) receptor-Gi1 protein complex
Fitted models: 8fy8
Deposition Authors: Warren AL
,
Zilberg G,
Capper MJ ,
Wacker D
Sample: Serotonin 1A (5-HT1A) receptor-Gi1 protein complex
Fitted models: 8fy8
Deposition Authors: Warren AL
,
Zilberg G,
Capper MJ ,
Wacker D
Structural pharmacology and therapeutic potential of 5-methoxytryptamines.
Warren AL ,
Lankri D ,
Cunningham MJ,
Serrano IC ,
Parise LF ,
Kruegel AC,
Duggan P ,
Zilberg G,
Capper MJ ,
Havel V ,
Russo SJ ,
Sames D ,
Wacker D
(2024) Nature , 630 , 237 - 246
,
Lankri D ,
Cunningham MJ,
Serrano IC ,
Parise LF ,
Kruegel AC,
Duggan P ,
Zilberg G,
Capper MJ ,
Havel V ,
Russo SJ ,
Sames D ,
Wacker D
(2024) Nature , 630 , 237 - 246
Grant Support:
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): GM 133504 (United States)
- Other private: Edward Mallinckrodt, Jr. Foundation
- Other private: Alfred P Sloan Foundationuroscience
- Other private: McKnight Foundation
- Other private: Irma T. Hirschl/Monique Weill-Caulier Trust