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EMD-29384

Single-particle
3.01 Å
EMD-29384
3D View Gallery
Deposition: 06/01/2023
Map released: 28/02/2024
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-29384
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8fqd summary report (pdf.gz) Map and 8fqd FULL report (pdf.gz)
EMICSS annotations (xml)

LBD conformation 1 (LBDconf1) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 10mM CaCl2, 140mM NMDG, 330uM CTZ, and 100mM L-glutamate (Open-Ca10)

EMD-29384

Single-particle
3.01 Å
EMD-29384
3D View Gallery
Deposition: 06/01/2023
Map released: 28/02/2024
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Rattus norvegicus
Sample: Homotetrameric assembly of GluA2 flip-Q isoform in complex with TARP gamma2 (K52E, K53E). Dimer-of-dimers assembly.
Fitted models: 8fqd

Deposition Authors: Nakagawa T
The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nakagawa T , Wang XT , Miguez-Cabello FJ , Bowie D
(2024) Nat Struct Mol Biol , 31 , 688 - 700
PUBMED: 38409505
DOI: doi:10.1038/s41594-024-01228-3
ISSN: 1545-9985