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EMD-29373

Single-particle
5.59 Å
EMD-29373
3D View Gallery
Deposition: 05/01/2023
Map released: 28/02/2024
Last modified: 01/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-29373
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8fq1 summary report (pdf.gz) Map and 8fq1 FULL report (pdf.gz)
EMICSS annotations (xml)

GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 150mM CaCl2, 330uM CTZ, and 100mM L-glutamate (Open-Ca150)

EMD-29373

Single-particle
5.59 Å
EMD-29373
3D View Gallery
Deposition: 05/01/2023
Map released: 28/02/2024
Last modified: 01/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Rattus norvegicus, Mus musculus
Sample: Homotetrameric assembly of GluA2 flip-Q isoform in complex with TARP gamma2 (K52E, K53E). Dimer-of-dimers assembly.
Fitted models: 8fq1

Deposition Authors: Nakagawa T
The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nakagawa T , Wang XT , Miguez-Cabello FJ , Bowie D
(2024) Nat Struct Mol Biol , 31 , 688 - 700
PUBMED: 38409505
DOI: doi:10.1038/s41594-024-01228-3
ISSN: 1545-9985