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EMD-29350

Single-particle
2.5 Å
EMD-29350 Deposition: 30/12/2022
Map released: 20/09/2023
Last modified: 16/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-29350

Native GABA-A receptor from the mouse brain, alpha1-beta2-gamma2 subtype, in complex with GABA and allopregnanolone

EMD-29350

Single-particle
2.5 Å
EMD-29350 Deposition: 30/12/2022
Map released: 20/09/2023
Last modified: 16/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus
Sample: Native GABAA Receptor isolated from mouse brain containing two alpha1 subunits, in complex with 8E3-Fab, GABA, and allopregnanolone
Fitted models: 8foi

Deposition Authors: Sun C, Gouaux E
Cryo-EM structures reveal native GABA A receptor assemblies and pharmacology.
Sun C, Zhu H, Clark S, Gouaux E
(2023) Nature , 622 , 195 - 201
PUBMED: 37730991
DOI: doi:10.1038/s41586-023-06556-w
ISSN: 1476-4687
ASTM: NATUAS