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EMD-29344
Cryo-EM structure of human TRPV6 in the open state
EMD-29344
Single-particle2.71 Å
Deposition: 30/12/2022Map released: 24/05/2023
Last modified: 19/06/2024
Sample Organism:
Homo sapiens
Sample: sample 1
Fitted models: 8fob
Deposition Authors: Neuberger A
,
Yelshanskaya MV,
Nadezhdin KD
,
Sobolevsky AI
Sample: sample 1
Fitted models: 8fob
Deposition Authors: Neuberger A
,
Yelshanskaya MV,
Nadezhdin KD
,
Sobolevsky AI
Structural mechanism of human oncochannel TRPV6 inhibition by the natural phytoestrogen genistein.
Neuberger A
,
Trofimov YA
,
Yelshanskaya MV,
Nadezhdin KD
,
Krylov NA
,
Efremov RG,
Sobolevsky AI
(2023) Nat Commun , 14 , 2659 - 2659
,
Trofimov YA
,
Yelshanskaya MV,
Nadezhdin KD
,
Krylov NA
,
Efremov RG,
Sobolevsky AI
(2023) Nat Commun , 14 , 2659 - 2659
Grant Support:
- National Institutes of Health/National Cancer Institute (NIH/NCI): R01 CA206573 (United States)
- National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS): R01 NS083660 (United States)
- National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS): R01 NS107253 (United States)
- National Institutes of Health/National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIH/NIAMS): R01 AR078814 (United States)
- German Research Foundation (DFG): 464295817 (Germany)
