EMD-29340

Single-particle
3.52 Å
EMD-29340
3D View Gallery
Deposition: 29/12/2022
Map released: 17/01/2024
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-29340

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8fo7 summary report (pdf.gz) Map-8fo7 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of LRRK2 bound to type I inhibitor LRRK2-IN-1

EMD-29340

Single-particle
3.52 Å
EMD-29340
3D View Gallery
Deposition: 29/12/2022
Map released: 17/01/2024
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: LRRK2-LRRK2-IN-1
Fitted models: 8fo7

Deposition Authors: Zhu H, Sun J
Pharmacology of LRRK2 with type I and II kinase inhibitors revealed by cryo-EM.
Zhu H, Hixson P, Ma W , Sun J
(2024) Cell Discov , 10 , 10 - 10
PUBMED: 38263358
DOI: doi:10.1038/s41421-023-00639-8
ISSN: 2056-5968