EMD-29285
Human PTH1R in complex with Abaloparatide and Gs
EMD-29285
Single-particle3.09 Å
Deposition: 22/12/2022Map released: 26/04/2023
Last modified: 14/06/2023
Sample Organism:
Homo sapiens,
Lama glama,
synthetic construct
Sample: Abaloparatide bound to the PTH1R in complex with G protein
Fitted models: 8fls
Deposition Authors: Cary BP
,
Belousoff MJ ,
Piper SJ ,
Wootten D ,
Sexton PM
Sample: Abaloparatide bound to the PTH1R in complex with G protein
Fitted models: 8fls
Deposition Authors: Cary BP
,
Belousoff MJ ,
Piper SJ ,
Wootten D ,
Sexton PM
Molecular insights into peptide agonist engagement with the PTH receptor.
Cary BP ,
Gerrard EJ ,
Belousoff MJ ,
Fletcher MM,
Jiang Y,
Russell IC ,
Piper SJ ,
Wootten D ,
Sexton PM
(2023) Structure , 31 , 668 - 676.e5
,
Gerrard EJ ,
Belousoff MJ ,
Fletcher MM,
Jiang Y,
Russell IC ,
Piper SJ ,
Wootten D ,
Sexton PM
(2023) Structure , 31 , 668 - 676.e5
Grant Support:
- Australian Research Council (ARC): IC200100052 (Australia)
- National Health and Medical Research Council (NHMRC, Australia): 1155302 (Australia)
- National Health and Medical Research Council (NHMRC, Australia): 1154434 (Australia)
- National Health and Medical Research Council (NHMRC, Australia): 1150083 (Australia)