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EMD-29283
Human PTH1R in complex with PTH(1-34) and Gs
EMD-29283
Single-particle2.55 Å
Deposition: 22/12/2022Map released: 26/04/2023
Last modified: 13/11/2024
Sample Organism:
Homo sapiens,
Lama glama
Sample: PTH bound to the PTH1R in complex with G protein
Fitted models: 8flq
Deposition Authors: Cary BP
,
Belousoff MJ ,
Piper SJ,
Wootten D ,
Sexton PM
Sample: PTH bound to the PTH1R in complex with G protein
Fitted models: 8flq
Deposition Authors: Cary BP
,
Belousoff MJ ,
Piper SJ,
Wootten D ,
Sexton PM
Molecular insights into peptide agonist engagement with the PTH receptor.
Cary BP ,
Gerrard EJ ,
Belousoff MJ ,
Fletcher MM,
Jiang Y,
Russell IC,
Piper SJ,
Wootten D ,
Sexton PM
(2023) Structure , 31 , 668 - 676.e5
,
Gerrard EJ ,
Belousoff MJ ,
Fletcher MM,
Jiang Y,
Russell IC,
Piper SJ,
Wootten D ,
Sexton PM
(2023) Structure , 31 , 668 - 676.e5
Grant Support:
- Australian Research Council (ARC): IC200100052 (Australia)
- National Health and Medical Research Council (NHMRC, Australia): 1155302 (Australia)
- National Health and Medical Research Council (NHMRC, Australia): 1154434 (Australia)
- National Health and Medical Research Council (NHMRC, Australia): 1150083 (Australia)