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EMD-29209
Structure of Bispecific CAP256V2LS-J3 Fab in complex with BG505 DS-SOSIP.664
EMD-29209
Single-particle3.18 Å
Deposition: 16/12/2022Map released: 01/02/2023
Last modified: 13/11/2024
Sample Organism:
Human immunodeficiency virus 1,
Lama glama,
Homo sapiens
Sample: CAP256V2LS-J3-3 Fab in complex with BG505 DS-SOSIP.664
Fitted models: 8fis
Deposition Authors: Gorman J
,
Kwong PD
Sample: CAP256V2LS-J3-3 Fab in complex with BG505 DS-SOSIP.664
Fitted models: 8fis
Deposition Authors: Gorman J
,
Kwong PD
Bispecific antibody CAP256.J3LS targets V2-apex and CD4-binding sites with high breadth and potency.
Zhang B,
Gorman J ,
Kwon YD,
Pegu A ,
Chao CW,
Liu T,
Asokan M,
Bender MF ,
Bylund T ,
Damron L ,
Gollapudi D,
Lei P,
Li Y,
Liu C,
Louder MK,
McKee K,
Olia AS,
Rawi R,
Schon A,
Wang S ,
Yang ES,
Yang Y,
Carlton K,
Doria-Rose NA,
Shapiro L,
Seaman MS,
Mascola JR,
Kwong PD
(2023) MABs , 15 , 2165390 - 2165390
,
Kwon YD,
Pegu A ,
Chao CW,
Liu T,
Asokan M,
Bender MF ,
Bylund T ,
Damron L ,
Gollapudi D,
Lei P,
Li Y,
Liu C,
Louder MK,
McKee K,
Olia AS,
Rawi R,
Schon A,
Wang S ,
Yang ES,
Yang Y,
Carlton K,
Doria-Rose NA,
Shapiro L,
Seaman MS,
Mascola JR,
Kwong PD
(2023) MABs , 15 , 2165390 - 2165390
Grant Support: