EMD-29097

Single-particle
2.95 Å
EMD-29097
3D View Gallery
Deposition: 14/12/2022
Map released: 15/02/2023
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-29097

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8fho summary report (pdf.gz) Map-8fho FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of human NCC (class 1)

EMD-29097

Single-particle
2.95 Å
EMD-29097
3D View Gallery
Deposition: 14/12/2022
Map released: 15/02/2023
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: NCC-polythiazide complex
Fitted models: 8fho

Deposition Authors: Zhang J , Fan M, Feng L
Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter.
Fan M, Zhang J , Lee CL, Zhang J , Feng L
(2023) Nature , 614 , 788 - 793
PUBMED: 36792826
DOI: doi:10.1038/s41586-023-05718-0
ISSN: 1476-4687
ASTM: NATUAS
Grant Support: