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EMD-29014

Single-particle
3.3 Å
EMD-29014
3D View Gallery
Deposition: 04/12/2022
Map released: 21/06/2023
Last modified: 15/11/2023
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-29014
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8fdu summary report (pdf.gz) Map and 8fdu FULL report (pdf.gz)
EMICSS annotations (xml)

Engineered human dynein motor domain in the microtubule-unbound state with LIS1 complex in the buffer containing ATP-Vi (local refined on AAA3-AAA5 and LIS1)

EMD-29014

Single-particle
3.3 Å
EMD-29014
3D View Gallery
Deposition: 04/12/2022
Map released: 21/06/2023
Last modified: 15/11/2023
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Engineered human dynein motor domain in microtubule-unbound state with LIS1 complex in the buffer containing ATP-Vi
Fitted models: 8fdu

Deposition Authors: Ton W, Wang Y , Chai P
Microtubule-binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport.
Ton WD, Wang Y , Chai P , Beauchamp-Perez C, Flint NT, Lammers LG, Xiong H, Zhang K , Markus SM
(2023) Nat Struct Mol Biol , 30 , 1365 - 1379
PUBMED: 37322240
DOI: doi:10.1038/s41594-023-01010-x
ISSN: 1545-9985