EMD-28888
CryoEM structure of designed modular protein oligomer C8-71
EMD-28888
Single-particle3.6 Å
Deposition: 17/11/2022Map released: 29/11/2023
Last modified: 16/10/2024
Sample Organism:
synthetic construct
Sample: Self-assembled homo-octamer of de novo designed protein C8-71
Fitted models: 8f6q
Deposition Authors: Redler RL, Edman NI
,
Baker D,
Ekiert D,
Bhabha G
Sample: Self-assembled homo-octamer of de novo designed protein C8-71
Fitted models: 8f6q
Deposition Authors: Redler RL, Edman NI
,
Baker D,
Ekiert D,
Bhabha G
Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies.
Edman NI ,
Phal A ,
Redler RL,
Schlichthaerle T ,
Srivatsan SR,
Ehnes DD,
Etemadi A,
An SJ,
Favor A,
Li Z,
Praetorius F,
Gordon M,
Vincent T,
Marchiano S ,
Blakely L,
Lin C,
Yang W,
Coventry B,
Hicks DR,
Cao L,
Bethel N,
Heine P,
Murray A,
Gerben S,
Carter L ,
Miranda M,
Negahdari B,
Lee S,
Trapnell C,
Zheng Y,
Murry CE,
Schweppe DK,
Freedman BS,
Stewart L,
Ekiert DC,
Schlessinger J,
Shendure J,
Bhabha G,
Ruohola-Baker H,
Baker D
(2024) Cell , 187 , 3726 - 3740.e43
,
Phal A ,
Redler RL,
Schlichthaerle T ,
Srivatsan SR,
Ehnes DD,
Etemadi A,
An SJ,
Favor A,
Li Z,
Praetorius F,
Gordon M,
Vincent T,
Marchiano S ,
Blakely L,
Lin C,
Yang W,
Coventry B,
Hicks DR,
Cao L,
Bethel N,
Heine P,
Murray A,
Gerben S,
Carter L ,
Miranda M,
Negahdari B,
Lee S,
Trapnell C,
Zheng Y,
Murry CE,
Schweppe DK,
Freedman BS,
Stewart L,
Ekiert DC,
Schlessinger J,
Shendure J,
Bhabha G,
Ruohola-Baker H,
Baker D
(2024) Cell , 187 , 3726 - 3740.e43
Secondary citations:
- Edman NI, Redler RL, Phal A, Schlichthaerle T, Srivatsan SR, Etemadi A, An SJ, Favor A, Ehnes D, Li Z, Praetorius F, Gordon M, Yang W, Coventry B, Hicks DR, Cao L, Bethel N, Heine P, Murray A, Gerben S, Carter L, Miranda M, Negahdari B, Lee S, Trapnell C, Stewart L, Ekiert DC, Schlessinger J, Shendure J, Bhabha G, Ruohola-Baker H & Baker D. (2023) Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies. bioRxiv,
- Edman NI, Redler RL, Phal A, Schlichthaerle T, Srivatsan SR, Etemadi A, An SJ, Favor A, Ehnes D, Li Z, Praetorius F, Gordon M, Yang W, Coventry B, Hicks DR, Cao L, Bethel N, Heine P, Murray A, Gerben S, Carter L, Miranda M, Negahdari B, Lee S, Trapnell C, Stewart L, Ekiert DC, Schlessinger J, Shendure J, Bhabha G, Ruohola-Baker H & Baker D. (2024) Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies. Cell, 187, 1 - 16
Grant Support: