EMD-28854

Single-particle
3.27 Å
EMD-28854
3D View Gallery
Deposition: 10/11/2022
Map released: 22/03/2023
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-28854

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8f4b summary report (pdf.gz) Map-8f4b FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Bovine multidrug resistance protein 1 (MRP1) bound to cyclic peptide inhibitor 1 (CPI1)

EMD-28854

Single-particle
3.27 Å
EMD-28854
3D View Gallery
Deposition: 10/11/2022
Map released: 22/03/2023
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Bos taurus, synthetic construct
Sample: Bovine multidrug resistance protein 1 (MRP1) in complex with cyclic peptide inhibitor 1 (CPI1)
Fitted models: 8f4b

Deposition Authors: Pietz HL , Chen J
A macrocyclic peptide inhibitor traps MRP1 in a catalytically incompetent conformation.
Pietz HL , Abbas A , Johnson ZL, Oldham ML , Suga H, Chen J
(2023) PNAS , 120 , e2220012120 - e2220012120
PUBMED: 36893260
DOI: doi:10.1073/pnas.2220012120
ISSN: 1091-6490
ASTM: PNASA6