Sample Organism: Homo sapiens
Sample: VSD4-NaV1.7-NaVPas channel chimera bound to the hybrid inhibitor GNE-1305
Fitted models: 8f0p

Deposition Authors: Kschonsak M , Jao CC, Arthur CP, Rohou AL, Bergeron P, Ortwine D, McKerall SJ, Hackos DH, Deng L, Chen J, Sutherlin D, Dragovich PS, Volgraf M, Wright MR, Payandeh J , Ciferri C , Tellis JC

Cryo-EM reveals an unprecedented binding site for Na V 1.7 inhibitors enabling rational design of potent hybrid inhibitors.