EMD-28693

Single-particle
4.0 Å
EMD-28693
3D View Gallery
Deposition: 28/10/2022
Map released: 09/11/2022
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-28693

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8eyr summary report (pdf.gz) Map-8eyr FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of two IGF1 bound full-length mouse IGF1R mutant (four glycine residues inserted in the alpha-CT; IGF1R-P674G4): symmetric conformation

EMD-28693

Single-particle
4.0 Å
EMD-28693
3D View Gallery
Deposition: 28/10/2022
Map released: 09/11/2022
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus, Homo sapiens
Sample: Two IGF1 bound full-length mouse IGF1R mutant (four glycine residues inserted in the alpha-CT; IGF1R-P674G4): symmetric conformation
Fitted models: 8eyr

Deposition Authors: Li J , Wu JY, Hall C, Bai XC, Choi E
Molecular basis for the role of disulfide-linked alpha CTs in the activation of insulin-like growth factor 1 receptor and insulin receptor.
Li J , Wu J , Hall C, Bai XC, Choi E
(2022) eLife , 11
PUBMED: 36413010
DOI: doi:10.7554/eLife.81286
ISSN: 2050-084X