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EMD-28547

Single-particle
3.64 Å
EMD-28547
3D View Gallery
Deposition: 09/10/2022
Map released: 31/07/2024
Last modified: 03/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-28547
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8eqv summary report (pdf.gz) Map and 8eqv FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of PRC2 in complex with the long isoform of AEBP2

EMD-28547

Single-particle
3.64 Å
EMD-28547
3D View Gallery
Deposition: 09/10/2022
Map released: 31/07/2024
Last modified: 03/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Ternary complex of PRC2 with long isoform of AEBP2
Fitted models: 8eqv

Deposition Authors: Boudes M , Zhang Q , Flanigan SF, Davidovich C
Auto-inhibition of PRC2 by the broadly expressed long isoform of AEBP2.
Mucha M , Lai Z , McKenzie NJ, Matra F, Boudes M , Flanigan SF, Alejo-Vinogradova MT, Monger C, Zhang Q , Nimmo D, Healy E, Silva AJ, Angelov D , Reck DM , Holland G , Atmaca ZE , King HE , Hamilton M, Glancy E, Nolan J , Weatheritt RJ , Bell O , Vermeulen M , Davidovich C , Bracken AP
(2025) EMBO J
PUBMED: 41168462
DOI: doi:10.1038/s44318-025-00616-9
ISSN: 1460-2075
ASTM: EMJODG