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EMD-28546
Structure of SARS-CoV-2 Orf3a in late endosome/lysosome-like environment, Saposin A nanodisc
EMD-28546
Single-particle2.8 Å
Deposition: 09/10/2022Map released: 08/02/2023
Last modified: 08/02/2023
Sample Organism:
Severe acute respiratory syndrome coronavirus 2,
Homo sapiens
Sample: Structure of SARS-CoV-2 Orf3a in late endosome/lysosome-like environment, Saposin A nanodisc
Fitted models: 8equ
Deposition Authors: Miller AN
,
Houlihan PR
,
Matamala E
,
Cabezas-Bratesco D
,
Lee GY
,
Cristofori-Armstrong B
,
Dilan TL
,
Sanchez-Martinez S
,
Matthies D
,
Yan R,
Yu Z,
Ren D
,
Brauchi SE
,
Clapham DE
Sample: Structure of SARS-CoV-2 Orf3a in late endosome/lysosome-like environment, Saposin A nanodisc
Fitted models: 8equ
Deposition Authors: Miller AN
,
Houlihan PR
,
Matamala E
,
Cabezas-Bratesco D
,
Lee GY
,
Cristofori-Armstrong B
,
Dilan TL
,
Sanchez-Martinez S
,
Matthies D
,
Yan R,
Yu Z,
Ren D
,
Brauchi SE
,
Clapham DE
The SARS-CoV-2 accessory protein Orf3a is not an ion channel, but does interact with trafficking proteins.
Miller AN
,
Houlihan PR
,
Matamala E
,
Cabezas-Bratesco D
,
Lee GY
,
Cristofori-Armstrong B
,
Dilan TL
,
Sanchez-Martinez S
,
Matthies D
,
Yan R,
Yu Z,
Ren D
,
Brauchi SE
,
Clapham DE
(2023) eLife , 12
,
Houlihan PR
,
Matamala E
,
Cabezas-Bratesco D
,
Lee GY
,
Cristofori-Armstrong B
,
Dilan TL
,
Sanchez-Martinez S
,
Matthies D
,
Yan R,
Yu Z,
Ren D
,
Brauchi SE
,
Clapham DE
(2023) eLife , 12
Grant Support:
- Howard Hughes Medical Institute (HHMI): (United States)
