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EMD-28160

Single-particle
2.8 Å
EMD-28160
3D View Gallery
Deposition: 15/09/2022
Map released: 19/10/2022
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-28160
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8eio summary report (pdf.gz) Map and 8eio FULL report (pdf.gz)
EMICSS annotations (xml)

The complex of phosphorylated human delta F508 cystic fibrosis transmembrane conductance regulator (CFTR) with elexacaftor (VX-445), lumacaftor (VX-809) and ATP/Mg

EMD-28160

Single-particle
2.8 Å
EMD-28160
3D View Gallery
Deposition: 15/09/2022
Map released: 19/10/2022
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: The complex of phosphorylated human delta F508 cystic fibrosis transmembrane conductance regulator (CFTR) with elexacaftor (VX-445), lumacaftor (VX-809) and ATP/Mg
Fitted models: 8eio

Deposition Authors: Fiedorczuk K , Chen J
Molecular structures reveal synergistic rescue of Delta 508 CFTR by Trikafta modulators.
Fiedorczuk K , Chen J
(2022) Science , 378 , 284 - 290
PUBMED: 36264792
DOI: doi:10.1126/science.ade2216
ISSN: 1095-9203
ASTM: SCIEAS
Grant Support: