EMD-27983
Structure of the full-length IP3R1 channel determined in the presence of Calcium/IP3/ATP
EMD-27983
Single-particle3.5 Å
Deposition: 29/08/2022Map released: 23/11/2022
Last modified: 23/10/2024
Sample Organism:
Rattus norvegicus
Sample: Type 1 inositol 1,4,5-trisphosphate receptor tetrameric protein complex
Fitted models: 8ear
Deposition Authors: Fan G, Baker MR
,
Terry LE ,
Arige V,
Chen M ,
Seryshev AB,
Baker ML,
Ludtke SJ,
Yule DI ,
Serysheva II
Sample: Type 1 inositol 1,4,5-trisphosphate receptor tetrameric protein complex
Fitted models: 8ear
Deposition Authors: Fan G, Baker MR
,
Terry LE ,
Arige V,
Chen M ,
Seryshev AB,
Baker ML,
Ludtke SJ,
Yule DI ,
Serysheva II
Conformational motions and ligand-binding underlying gating and regulation in IP 3 R channel.
Fan G,
Baker MR ,
Terry LE ,
Arige V,
Chen M ,
Seryshev AB,
Baker ML,
Ludtke SJ,
Yule DI ,
Serysheva II
(2022) Nat Commun , 13 , 6942 - 6942
,
Terry LE ,
Arige V,
Chen M ,
Seryshev AB,
Baker ML,
Ludtke SJ,
Yule DI ,
Serysheva II
(2022) Nat Commun , 13 , 6942 - 6942
Grant Support:
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R01GM072804 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R01GM080139 (United States)
- National Institutes of Health/National Institute of Dental and Craniofacial Research (NIH/NIDCR): DE019245 (United States)
- Welch Foundation: AU-2014-20190330 (United States)
- Welch Foundation: AU-2014-20220331 (United States)
- American Heart Association: 18CDA34110086 (United States)
- Cancer Prevention and Research Institute of Texas (CPRIT): RP190602 (United States)