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EMD-27966

Single-particle
2.69 Å
EMD-27966
3D View Gallery
Deposition: 27/08/2022
Map released: 30/11/2022
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-27966
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8e9w summary report (pdf.gz) Map and 8e9w FULL report (pdf.gz)
EMICSS annotations (xml)

CryoEM structure of miniGq-coupled hM3Dq in complex with DCZ

EMD-27966

Single-particle
2.69 Å
EMD-27966
3D View Gallery
Deposition: 27/08/2022
Map released: 30/11/2022
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: Gq-coupled hM3R complex
Fitted models: 8e9w

Deposition Authors: Zhang S , Fay JF , Roth BL
Molecular basis for selective activation of DREADD-based chemogenetics.
Zhang S , Gumpper RH, Huang XP, Liu Y , Krumm BE , Cao C , Fay JF , Roth BL
(2022) Nature , 612 , 354 - 362
PUBMED: 36450989
DOI: doi:10.1038/s41586-022-05489-0
ISSN: 1476-4687
ASTM: NATUAS