Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-27894

Single-particle
3.43 Å
EMD-27894
3D View Gallery
Deposition: 18/08/2022
Map released: 26/10/2022
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-27894
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8e4o summary report (pdf.gz) Map and 8e4o FULL report (pdf.gz)
EMICSS annotations (xml)

The closed C1-state mouse TRPM8 structure in complex with putative PI(4,5)P2

EMD-27894

Single-particle
3.43 Å
EMD-27894
3D View Gallery
Deposition: 18/08/2022
Map released: 26/10/2022
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus
Sample: Transient receptor potential cation channel subfamily M member 8
Fitted models: 8e4o

Deposition Authors: Yin Y , Zhang F, Feng S , Butay KJ , Borgnia MJ , Im W , Lee S-Y
Activation mechanism of the mouse cold-sensing TRPM8 channel by cooling agonist and PIP 2.
Yin Y , Zhang F, Feng S , Butay KJ , Borgnia MJ , Im W , Lee SY
(2022) Science , 378 , eadd1268 - eadd1268
PUBMED: 36227998
DOI: doi:10.1126/science.add1268
ISSN: 1095-9203
ASTM: SCIEAS