EMD-27872
Cryo-EM structure of the PAC1R-PACAP27-Gs complex
EMD-27872
Single-particle2.3 Å
Deposition: 17/08/2022Map released: 23/11/2022
Last modified: 14/05/2025
Sample Organism:
Homo sapiens,
Lama glama
Sample: Gs coupled Pituitary adenylate cyclase-activating polypeptide type I receptor complex with PACAP27 peptide
Fitted models: 8e3x
Deposition Authors: Piper SJ
,
Danev R ,
Sexton P,
Wootten D
Sample: Gs coupled Pituitary adenylate cyclase-activating polypeptide type I receptor complex with PACAP27 peptide
Fitted models: 8e3x
Deposition Authors: Piper SJ
,
Danev R ,
Sexton P,
Wootten D
Understanding VPAC receptor family peptide binding and selectivity.
Piper SJ ,
Deganutti G ,
Lu J,
Zhao P ,
Liang YL,
Lu Y,
Fletcher MM ,
Hossain MA ,
Christopoulos A ,
Reynolds CA ,
Danev R ,
Sexton PM ,
Wootten D
(2022) Nat Commun , 13 , 7013 - 7013
,
Deganutti G ,
Lu J,
Zhao P ,
Liang YL,
Lu Y,
Fletcher MM ,
Hossain MA ,
Christopoulos A ,
Reynolds CA ,
Danev R ,
Sexton PM ,
Wootten D
(2022) Nat Commun , 13 , 7013 - 7013
Grant Support:
- National Health and Medical Research Council (NHMRC, Australia): 1155302 (Australia)
- National Health and Medical Research Council (NHMRC, Australia): 1150083 (Australia)
- National Health and Medical Research Council (NHMRC, Australia): 1154434 (Australia)
- Royal Society: (United Kingdom)
- Japan Science and Technology: (Japan)