EMD-27810

Single-particle
4.1 Å
EMD-27810
3D View Gallery
Deposition: 08/08/2022
Map released: 30/08/2023
Last modified: 27/09/2023
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-27810

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8dzz summary report (pdf.gz) Map-8dzz FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of chi dynein bound to Lis1

EMD-27810

Single-particle
4.1 Å
EMD-27810
3D View Gallery
Deposition: 08/08/2022
Map released: 30/08/2023
Last modified: 27/09/2023
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Saccharomyces cerevisiae
Sample: Cytoplasmic dynein-1(E2448Q) bound to Lis1 in chi conformation
Fitted models: 8dzz

Deposition Authors: Reimer JM, Lahiri I, Leschziner AE
Lis1 relieves cytoplasmic dynein-1 autoinhibition by acting as a molecular wedge.
Karasmanis EP , Reimer JM, Kendrick AA , Nguyen KHV, Rodriguez JA, Truong JB , Lahiri I, Reck-Peterson SL , Leschziner AE
(2023) Nat Struct Mol Biol , 30 , 1357 - 1364
PUBMED: 37620585
DOI: doi:10.1038/s41594-023-01069-6
ISSN: 1545-9985