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EMD-27753

Single-particle
2.71 Å
EMD-27753
3D View Gallery
Deposition: 01/08/2022
Map released: 02/11/2022
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-27753
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8dwg summary report (pdf.gz) Map and 8dwg FULL report (pdf.gz)
EMICSS annotations (xml)

CryoEM structure of Gq-coupled MRGPRX1 with peptide ligand BAM8-22 and positive allosteric modulator ML382

EMD-27753

Single-particle
2.71 Å
EMD-27753
3D View Gallery
Deposition: 01/08/2022
Map released: 02/11/2022
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Bos taurus, Mus musculus
Sample: MRGPRX1-Gq BAM8-22
Fitted models: 8dwg

Deposition Authors: Liu Y , Cao C , Fay JF , Roth BL
Ligand recognition and allosteric modulation of the human MRGPRX1 receptor.
Liu Y , Cao C , Huang XP, Gumpper RH, Rachman MM , Shih SL , Krumm BE , Zhang S , Shoichet BK , Fay JF , Roth BL
(2023) Nat Chem Biol , 19 , 416 - 422
PUBMED: 36302898
DOI: doi:10.1038/s41589-022-01173-6
ISSN: 1552-4469