EMD-27731

Single-particle
3.5 Å
EMD-27731
3D View Gallery
Deposition: 27/07/2022
Map released: 31/08/2022
Last modified: 30/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-27731
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8dv2 summary report (pdf.gz) Map and 8dv2 FULL report (pdf.gz)
EMICSS annotations (xml)

SARS-CoV-2 Wuhan-hu-1-Spike-RBD bound to computationally engineered ACE2 mimetic CVD293

EMD-27731

Single-particle
3.5 Å
EMD-27731
3D View Gallery
Deposition: 27/07/2022
Map released: 31/08/2022
Last modified: 30/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Severe acute respiratory syndrome coronavirus 2, Homo sapiens
Sample: SARS-CoV-2 Wuhan-hu-1-Spike bound to linker variant of affinity matured ACE2 mimetic CVD293
Fitted models: 8dv2

Deposition Authors: QCRG Structural Biology Consortium, Remesh SG, Merz GE, Brilot AF, Chio U, Verba KA
Computational pipeline provides mechanistic understanding of Omicron variant of concern neutralizing engineered ACE2 receptor traps.
Remesh SG, Merz GE, Brilot AF, Chio US, Rizo AN, Pospiech Jr TH, Lui I, Laurie MT, Glasgow J, Le CQ, Zhang Y, Diwanji D, Hernandez E, Lopez J , Mehmood H , Pawar KI, Pourmal S, Smith AM, Zhou F, DeRisi J, Kortemme T, Rosenberg OS, Glasgow A, Leung KK, Wells JA, Verba KA
(2023) Structure , 31 , 253
PUBMED: 36805129
DOI: doi:10.1016/j.str.2023.01.009
ISSN: 0969-2126
ASTM: STRUE6