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EMD-27728

Helical reconstruction
3.2 Å
EMD-27728
3D View Gallery
Deposition: 27/07/2022
Map released: 02/08/2023
Last modified: 14/02/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-27728
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8duw summary report (pdf.gz) Map and 8duw FULL report (pdf.gz)
EMICSS annotations (xml)

HnRNPA2 D290V LCD PM2

EMD-27728

Helical reconstruction
3.2 Å
EMD-27728
3D View Gallery
Deposition: 27/07/2022
Map released: 02/08/2023
Last modified: 14/02/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Fibrils of hnRNPA2 D290V LCD PM2
Fitted models: 8duw

Deposition Authors: Eisenberg DS, Lu J , Ge P , Boyer DR
Cryo-EM structures of the D290V mutant of the hnRNPA2 low-complexity domain suggests how D290V affects phase separation and aggregation.
Lu J , Ge P , Sawaya MR , Hughes MP, Boyer DR, Cao Q, Abskharon R, Cascio D, Tayeb-Fligelman E, Eisenberg DS
(2023) J Biol Chem , 300 , 105531 - 105531
PUBMED: 38072051
DOI: doi:10.1016/j.jbc.2023.105531
ISSN: 1083-351X
ASTM: JBCHA3