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EMD-27691
eEF1A(GDP)aa-tRNA stalled on the human 80S ribosome by didemnin B
EMD-27691
Single-particle3.6 Å
Deposition: 25/07/2022Map released: 26/10/2022
Last modified: 17/01/2024
Sample Organism:
Escherichia coli,
Homo sapiens,
Oryctolagus cuniculus
Sample: eEF1A(GDP)aa-tRNA stalled on the human 80S ribosome by didemnin B
Deposition Authors: Rundlet EJ
,
Juette MF ,
Blanchard SC ,
Ferguson A,
Taunton J ,
Carelli JD
Sample: eEF1A(GDP)aa-tRNA stalled on the human 80S ribosome by didemnin B
Deposition Authors: Rundlet EJ
,
Juette MF ,
Blanchard SC ,
Ferguson A,
Taunton J ,
Carelli JD
Didemnin B and ternatin-4 differentially inhibit conformational changes in eEF1A required for aminoacyl-tRNA accommodation into mammalian ribosomes.
Juette MF ,
Carelli JD ,
Rundlet EJ ,
Brown A ,
Shao S ,
Ferguson A,
Wasserman MR,
Holm M,
Taunton J ,
Blanchard SC
(2022) eLife , 11
,
Carelli JD ,
Rundlet EJ ,
Brown A ,
Shao S ,
Ferguson A,
Wasserman MR,
Holm M,
Taunton J ,
Blanchard SC
(2022) eLife , 11
Grant Support: