EMD-27635

Single-particle
3.2 Å
EMD-27635
3D View Gallery
Deposition: 15/07/2022
Map released: 24/08/2022
Last modified: 17/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-27635

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8dph summary report (pdf.gz) Map-8dph FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of the 5HT2C receptor (VGV isoform) bound to lorcaserin

EMD-27635

Single-particle
3.2 Å
EMD-27635
3D View Gallery
Deposition: 15/07/2022
Map released: 24/08/2022
Last modified: 17/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: 5-ht2c heterotrimeric complex (VGV isoform)
Fitted models: 8dph

Deposition Authors: Gumpper RH, Fay JF, Roth BL
Molecular insights into the regulation of constitutive activity by RNA editing of 5HT 2C serotonin receptors.
Gumpper RH, Fay JF, Roth BL
(2022) Cell Rep , 40 , 111211 - 111211
PUBMED: 35977511
DOI: doi:10.1016/j.celrep.2022.111211
ISSN: 2211-1247