EMD-27436

Single-particle
2.73 Å
EMD-27436
3D View Gallery
Deposition: 27/06/2022
Map released: 23/11/2022
Last modified: 12/06/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-27436

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8dhm summary report (pdf.gz) Map-8dhm FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Human TMEM175 in complex with 4-aminopyridine

EMD-27436

Single-particle
2.73 Å
EMD-27436
3D View Gallery
Deposition: 27/06/2022
Map released: 23/11/2022
Last modified: 12/06/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human TMEM175
Fitted models: 8dhm

Deposition Authors: Oh S , Hite RK
Mechanism of 4-aminopyridine inhibition of the lysosomal channel TMEM175.
Oh S , Stix R, Zhou W, Faraldo-Gomez JD , Hite RK
(2022) PNAS , 119 , e2208882119 - e2208882119
PUBMED: 36279431
DOI: doi:10.1073/pnas.2208882119
ISSN: 1091-6490
ASTM: PNASA6