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EMD-27436

Single-particle
2.73 Å
EMD-27436 Deposition: 27/06/2022
Map released: 23/11/2022
Last modified: 23/11/2022
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-27436

Human TMEM175 in complex with 4-aminopyridine

EMD-27436

Single-particle
2.73 Å
EMD-27436 Deposition: 27/06/2022
Map released: 23/11/2022
Last modified: 23/11/2022
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Homo sapiens
Sample: Human TMEM175
Fitted models: 8dhm ()

Deposition Authors: Oh S , Hite RK
Mechanism of 4-aminopyridine inhibition of the lysosomal channel TMEM175.
Oh S , Stix R, Zhou W, Faraldo-Gomez JD , Hite RK
(2022) PNAS , 119 , e2208882119 - e2208882119
PUBMED: 36279431
DOI: doi:10.1073/pnas.2208882119
ISSN: 1091-6490
ASTM: PNASA6