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EMD-27320
Cryo-EM structure of CasLambda (Cas12l) bound to crRNA and DNA
EMD-27320
Single-particle2.99 Å
Deposition: 15/06/2022Map released: 14/12/2022
Last modified: 12/06/2024
Sample Organism:
uncultured virus
Sample: CasLambda-crRNA-dsDNA ternary structure
Fitted models: 8dc2
Deposition Authors: Al-Shayeb B
,
Skopintsev P
,
Soczek K,
Doudna J
Sample: CasLambda-crRNA-dsDNA ternary structure
Fitted models: 8dc2
Deposition Authors: Al-Shayeb B
,
Skopintsev P
,
Soczek K,
Doudna J
Diverse virus-encoded CRISPR-Cas systems include streamlined genome editors.
Al-Shayeb B
,
Skopintsev P
,
Soczek KM,
Stahl EC,
Li Z,
Groover E,
Smock D,
Eggers AR
,
Pausch P,
Cress BF,
Huang CJ,
Staskawicz B,
Savage DF,
Jacobsen SE,
Banfield JF,
Doudna JA
(2022) Cell , 185 , 4574 - 4586.e16
,
Skopintsev P
,
Soczek KM,
Stahl EC,
Li Z,
Groover E,
Smock D,
Eggers AR
,
Pausch P,
Cress BF,
Huang CJ,
Staskawicz B,
Savage DF,
Jacobsen SE,
Banfield JF,
Doudna JA
(2022) Cell , 185 , 4574 - 4586.e16
Grant Support:
- National Science Foundation (NSF, United States): (United States)
- Swiss National Science Foundation: P2EZP3_195621 (Switzerland)
