EMD-27291

Single-particle
2.4 Å
EMD-27291
3D View Gallery
Deposition: 14/06/2022
Map released: 15/02/2023
Last modified: 12/06/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-27291
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8dbn summary report (pdf.gz) Map and 8dbn FULL report (pdf.gz)
EMICSS annotations (xml)

Human PRPS1-E307A engineered mutation with Phosphate, ATP, and R5P; Hexamer

EMD-27291

Single-particle
2.4 Å
EMD-27291
3D View Gallery
Deposition: 14/06/2022
Map released: 15/02/2023
Last modified: 12/06/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Hexamer of phosphoribosyl pyrophosphate synthetase 1 E307A engineered mutation with phosphate, ATP, and R5P
Fitted models: 8dbn

Deposition Authors: Hvorecny KL, Kollman JM
Human PRPS1 filaments stabilize allosteric sites to regulate activity.
Hvorecny KL, Hargett K, Quispe JD, Kollman JM
(2023) Nat Struct Mol Biol , 30 , 391 - 402
PUBMED: 36747094
DOI: doi:10.1038/s41594-023-00921-z
ISSN: 1545-9985