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EMD-27227

Single-particle
3.03 Å
EMD-27227
3D View Gallery
Deposition: 07/06/2022
Map released: 29/03/2023
Last modified: 30/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-27227
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8d74 summary report (pdf.gz) Map and 8d74 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM map of human CNTF signaling complex with full extracellular domains: refined from selected full particle dataset, with better resolution in the interaction core region

EMD-27227

Single-particle
3.03 Å
EMD-27227
3D View Gallery
Deposition: 07/06/2022
Map released: 29/03/2023
Last modified: 30/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human CNTF in complex with CNTFR alpha, gp130, and LIFR
Fitted models: 8d74

Deposition Authors: Zhou Y , Franklin MC
Structural insights into the assembly of gp130 family cytokine signaling complexes.
Zhou Y , Stevis PE, Cao J, Saotome K, Wu J , Glatman Zaretsky A , Haxhinasto S , Yancopoulos GD, Murphy AJ , Sleeman MW , Olson WC, Franklin MC
(2023) Sci Adv , 9 , eade4395 - eade4395
PUBMED: 36930708
DOI: doi:10.1126/sciadv.ade4395
ISSN: 2375-2548
Grant Support: