EMD-27098

Single-particle
2.22 Å
EMD-27098
3D View Gallery
Deposition: 24/05/2022
Map released: 07/09/2022
Last modified: 12/06/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-27098

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8czi summary report (pdf.gz) Map-8czi FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with extended HR2

EMD-27098

Single-particle
2.22 Å
EMD-27098
3D View Gallery
Deposition: 24/05/2022
Map released: 07/09/2022
Last modified: 12/06/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Severe acute respiratory syndrome coronavirus 2
Sample: SARS-CoV-2 HR1HR2 complex
Fitted models: 8czi

Deposition Authors: Yang K , Brunger AT
Nanomolar inhibition of SARS-CoV-2 infection by an unmodified peptide targeting the prehairpin intermediate of the spike protein.
Yang K , Wang C , Kreutzberger AJB, Ojha R , Kuivanen S, Couoh-Cardel S , Muratcioglu S, Eisen TJ, White KI , Held RG , Subramanian S , Marcus K , Pfuetzner RA, Esquivies L , Doyle CA , Kuriyan J, Vapalahti O , Balistreri G , Kirchhausen T, Brunger AT
(2022) PNAS , 119 , e2210990119 - e2210990119
PUBMED: 36122200
DOI: doi:10.1073/pnas.2210990119
ISSN: 1091-6490
ASTM: PNASA6
Grant Support: