EMD-27028

Single-particle
2.84 Å
EMD-27028
3D View Gallery
Deposition: 19/05/2022
Map released: 15/03/2023
Last modified: 12/06/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-27028

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8cwo summary report (pdf.gz) Map-8cwo FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cutibacterium acnes 30S ribosomal subunit with Sarecycline bound, body domain only in the local refined map

EMD-27028

Single-particle
2.84 Å
EMD-27028
3D View Gallery
Deposition: 19/05/2022
Map released: 15/03/2023
Last modified: 12/06/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Cutibacterium acnes, Escherichia coli
Sample: 30S subunit body domain from 70S ribosome with mRNA, P-site tRNA and Sarecycline bound
Fitted models: 8cwo

Deposition Authors: Lomakin IB , Devarkar SC , Bunick CG
Sarecycline inhibits protein translation in Cutibacterium acnes 70S ribosome using a two-site mechanism.
Lomakin IB , Devarkar SC , Patel S, Grada A , Bunick CG
(2023) Nucleic Acids Res , 51 , 2915 - 2930
PUBMED: 36864821
DOI: doi:10.1093/nar/gkad103
ISSN: 1362-4962
ASTM: NARHAD
Grant Support: