EMD-27009

Single-particle
2.66 Å
EMD-27009
3D View Gallery
Deposition: 18/05/2022
Map released: 15/03/2023
Last modified: 19/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-27009

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8cvm summary report (pdf.gz) Map-8cvm FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cutibacterium acnes 50S ribosomal subunit with P-site tRNA and Sarecycline bound in the local refined map

EMD-27009

Single-particle
2.66 Å
EMD-27009
3D View Gallery
Deposition: 18/05/2022
Map released: 15/03/2023
Last modified: 19/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Cutibacterium acnes, Escherichia coli
Sample: 50S subunit from 70S ribosome with mRNA, P-site tRNA and Sarecycline bound
Fitted models: 8cvm

Deposition Authors: Lomakin IB , Devarkar SC , Bunick CG
Sarecycline inhibits protein translation in Cutibacterium acnes 70S ribosome using a two-site mechanism.
Lomakin IB , Devarkar SC , Patel S, Grada A , Bunick CG
(2023) Nucleic Acids Res , 51 , 2915 - 2930
PUBMED: 36864821
DOI: doi:10.1093/nar/gkad103
ISSN: 1362-4962
ASTM: NARHAD
Grant Support: